MARCH8 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (34.58 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MARCH8.
Immunogen
MARCH8 (NP_659458, 77 a.a. ~ 153 a.a) partial recombinant protein with GST tag.
Sequence
QDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.58 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MARCH8
Entrez GeneID
220972GeneBank Accession#
NM_145021Protein Accession#
NP_659458Gene Name
MARCH8
Gene Alias
MARCH-VIII, MIR, RNF178, c-MIR
Gene Description
membrane-associated ring finger (C3HC4) 8
Gene Ontology
HyperlinkGene Summary
cellular modulator of immune recognition|cellular modulator of immune recognition|cellular modulator of immune recognition (c-MIR)|membrane-associated RING-CH protein VIII
Other Designations
OTTHUMP00000058921|c-mir, cellular modulator of immune recognition|cellular modulator of immune recognition|cellular modulator of immune recognition (c-MIR)|membrane-associated RING-CH protein VIII
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Interactome
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Disease
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Publication Reference
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MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.
Kumar S, Barouch-Bentov R, Xiao F, Schor S, Pu S, Biquand E, Lu A, Lindenbach BD, Jacob Y, Demeret C, Einav S.
Cell Reports 2019 Feb; 26(7):1800.
Application：IF, WB, Human, Huh7, 293T cells.
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MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins.
Tada T, Zhang Y, Koyama T, Tobiume M, Tsunetsugu-Yokota Y, Yamaoka S, Fujita H, Tokunaga K.
Nature Medicine 2015 Dec; 21(12):1502.
Application：WB-Ce, Human, 293T, MAGIC5 cells.
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MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.
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