ATOH7 monoclonal antibody (M01), clone 1A5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ATOH7.
Immunogen
ATOH7 (NP_660161, 53 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEA
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.06 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ATOH7 expression in transfected 293T cell line by ATOH7 monoclonal antibody (M01), clone 1A5.
Lane 1: ATOH7 transfected lysate(16.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — ATOH7
Entrez GeneID
220202GeneBank Accession#
NM_145178Protein Accession#
NP_660161Gene Name
ATOH7
Gene Alias
Math5, bHLHa13
Gene Description
atonal homolog 7 (Drosophila)
Omim ID
609875Gene Ontology
HyperlinkGene Summary
ATOH7 is a member of the family of basic helix-loop-helix (bHLH) proteins with similarity to Drosophila 'atonal,' a proneural bHLH gene that controls photoreceptor development (Brown et al., 2002 [PubMed 11889557]).[supplied by OMIM
Other Designations
OTTHUMP00000019697|atonal homolog 7
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Disease
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Publication Reference
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ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous.
Prasov L, Masud T, Khaliq S, Mehdi SQ, Abid A, Oliver ER, Silva ED, Lewanda A, Brodsky MC, Borchert M, Kelberman D, Sowden JC, Dattani MT, Glaser T.
Human Molecular Genetics 2012 Aug; 21(16):3681.
Application:Func, Human, HEK 293T cells.
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ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous.
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