NALP11 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
SDS-PAGE Gel
NLRP11 transfected lysate.
Western Blot
Lane 1: NLRP11 transfected lysate ( 117.8 KDa)
Lane 2: Non-transfected lysate.
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-NALP11 full-length
Host
Human
Theoretical MW (kDa)
117.8
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NALP11 antibody (H00204801-B01) by Western Blots.
SDS-PAGE Gel
NLRP11 transfected lysate.
Western Blot
Lane 1: NLRP11 transfected lysate ( 117.8 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — NLRP11
Entrez GeneID
204801GeneBank Accession#
NM_145007Protein Accession#
NP_659444Gene Name
NLRP11
Gene Alias
CLR19.6, FLJ26273, NALP11, NOD17, PAN10, PYPAF6, PYPAF7
Gene Description
NLR family, pyrin domain containing 11
Omim ID
609664Gene Ontology
HyperlinkGene Summary
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Other Designations
NACHT, LRR and PYD containing protein 11|NACHT, leucine rich repeat and PYD containing 11|PAAD- and NACHT-containing protein 10|PAAD- and NACHT-containing protein 10B|PYRIN-containing APAF1-like protein 6|nucleotide-binding oligomerization domain, leucine
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com