SPRED2 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SPRED2.
Immunogen
SPRED2 (NP_861449, 120 a.a. ~ 219 a.a) partial recombinant protein with GST tag.
Sequence
EDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMPRPCRQVSFPDDDEEIVRINP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SPRED2
Entrez GeneID
200734GeneBank Accession#
NM_181784Protein Accession#
NP_861449Gene Name
SPRED2
Gene Alias
FLJ21897, FLJ31917, MGC163164, Spred-2
Gene Description
sprouty-related, EVH1 domain containing 2
Omim ID
609292Gene Ontology
HyperlinkGene Summary
SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM
Other Designations
sprouty protein with EVH-1 domain 2, related sequence|sprouty-related protein with EVH-1 domain 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Direct Association of Sprouty-related Protein with an EVH1 Domain (SPRED) 1 or SPRED2 with DYRK1A Modifies Substrate/Kinase Interactions.
Li D, Jackson RA, Yusoff P, Guy GR.
The Journal of Biological Chemistry 2010 Nov; 285(46):35374.
Application:IP, WB-Tr, Human, PC-3 cells.
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Direct Association of Sprouty-related Protein with an EVH1 Domain (SPRED) 1 or SPRED2 with DYRK1A Modifies Substrate/Kinase Interactions.
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