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DAND5 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00199699-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human DAND5 protein.
  • Immunogen:
  • DAND5 (ADR82845.1, 1 a.a. ~ 189 a.a) full-length human protein.
  • Sequence:
  • MLLGQLSTLLCLLSGALPTGSGRPEPQSPRPQSWAAANQTWALGPGALPPLVPASALGSWKAFLGLQKARQLGMGRLQRGQDEVAAVTLPLNPQEVIQGMCKAVPFVQVFSRPGCSAIRLRNHLCFGHCSSLYIPGSDPTPLVLCNSCMPARKRWAPVVLWCLTGSSASRRRVKISTMLIEGCHCSPKA
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Gene Name:
  • DAND5
  • Gene Alias:
  • CER2,CERL2,CKTSF1B3,COCO,CRL2,DANTE,GREM3,MGC126849,SP1
  • Gene Description:
  • DAN domain family, member 5
  • Gene Summary:
  • This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq
  • Other Designations:
  • cerberus 2,cerberus-like 2,cysteine knot superfamily 1, BMP antagonist 3,dante
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