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Last updated: 2017/8/13

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UBR1 Pre-design Chimera RNAi

  • Catalog # : H00197131-R01
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  • Specification
  • Product Description:
  • Homo sapiens ubiquitin protein ligase E3 component n-recognin 1 (UBR1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_174916
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • UBR1
  • Gene Alias:
  • JBS,MGC142065,MGC142067
  • Gene Description:
  • ubiquitin protein ligase E3 component n-recognin 1
  • Gene Summary:
  • The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq
  • Other Designations:
  • E3a ligase,ubiquitin ligase E3 alpha-I,ubiquitin-protein ligase E3-alpha
  • Related Disease
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