UBR1 polyclonal antibody (A01)

Catalog # H00197131-A01

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Quantity

Size:50 uL
Price: USD $ 243.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

UBR1 polyclonal antibody (A01), Lot # 060802QCS1 Western Blot analysis of UBR1 expression in K-562 ( Cat # L009V1 ).

QC Test

Western Blot detection against Immunogen (37 KDa) .

  • Specification

    Product Description

    Mouse polyclonal antibody raised against a partial recombinant UBR1.

    Immunogen

    UBR1 (NP_777576, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag.

    Sequence

    ADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG

    Host

    Mouse

    Reactivity

    Human

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (37 KDa) .

    Storage Buffer

    50 % glycerol

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Cell lysate)

    UBR1 polyclonal antibody (A01), Lot # 060802QCS1 Western Blot analysis of UBR1 expression in K-562 ( Cat # L009V1 ).

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — UBR1

    Entrez GeneID

    197131

    GeneBank Accession#

    NM_17491

    Protein Accession#

    NP_777576

    Gene Name

    UBR1

    Gene Alias

    JBS, MGC142065, MGC142067

    Gene Description

    ubiquitin protein ligase E3 component n-recognin 1

    Omim ID

    243800 605981

    Gene Ontology

    Hyperlink

    Gene Summary

    The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq

    Other Designations

    E3a ligase|ubiquitin ligase E3 alpha-I|ubiquitin-protein ligase E3-alpha

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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