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Western Blot (Transfected lysate)

Western Blot analysis of ADAMTS18 expression in transfected 293T cell line (H00170692-T01) by ADAMTS18 MaxPab polyclonal antibody.

Lane 1: ADAMTS18 transfected lysate(134.31 KDa).
Lane 2: Non-transfected lysate.

Entrez GeneID

170692

GeneBank Accession#

BC063283.1

Protein Accession#

AAH63283.1

Gene Name

ADAMTS18

Gene Alias

ADAMTS21

Gene Description

ADAM metallopeptidase with thrombospondin type 1 motif, 18

Omim ID

607512

Gene Ontology

Hyperlink

Gene Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq

Other Designations

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21|disintegrin and metalloprotease-like protein