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Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

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Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

IL28RA

Gene Alias

CRF2/12, IFNLR, IFNLR1, IL-28R1, LICR2

Gene Description

interleukin 28 receptor, alpha (interferon, lambda receptor)

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

Other Designations

OTTHUMP00000003067|OTTHUMP00000003068|OTTHUMP00000003069|class II cytokine receptor CRF2/12|interferon lambda, receptor 1|interleukin 28 receptor A|interleukin 28 receptor, alpha|interleukin or cytokine receptor 2