SPRED1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SPRED1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SPRED1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SPRED1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SPRED1
Entrez GeneID
161742GeneBank Accession#
SPRED1Gene Name
SPRED1
Gene Alias
FLJ33903, NFLS
Gene Description
sprouty-related, EVH1 domain containing 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq
Other Designations
EVH1/Sprouty domain containing protein|sprouty-related protein 1 with EVH-1 domain|suppressor of Ras/MAPK activation
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