SPRED1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SPRED1 expression in transfected 293T cell line (H00161742-T02) by SPRED1 MaxPab polyclonal antibody.
Lane 1: SPRED1 transfected lysate(50.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SPRED1 protein.
Immunogen
SPRED1 (NP_689807.1, 1 a.a. ~ 444 a.a) full-length human protein.
Sequence
MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFIRGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISQGCPESKNEAEGADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRPSPFEDLNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIRHVSFQDEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDADSSIQFSKPDSKKSDYLYSCGDETKLSSPKDSVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEENVRGKCQDAPDPIKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAAG
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SPRED1 expression in transfected 293T cell line (H00161742-T02) by SPRED1 MaxPab polyclonal antibody.
Lane 1: SPRED1 transfected lysate(50.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SPRED1
Entrez GeneID
161742GeneBank Accession#
NM_152594Protein Accession#
NP_689807.1Gene Name
SPRED1
Gene Alias
FLJ33903, NFLS
Gene Description
sprouty-related, EVH1 domain containing 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq
Other Designations
EVH1/Sprouty domain containing protein|sprouty-related protein 1 with EVH-1 domain|suppressor of Ras/MAPK activation
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Interactome
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Pathway
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Disease
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