DAB2IP monoclonal antibody (M04), clone 8C10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DAB2IP.
Immunogen
DAB2IP (NP_115941.1, 551 a.a. ~ 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KSLSMVDLQDARTLDGEAGSPAGPDVLPTDGQAAAAQLVAGWPARATPVNLAGLATVRRAGQTPTTPGTSEGAPGRPQLLAPLSFQNPVYQMAAGLPLSP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DAB2IP monoclonal antibody (M04), clone 8C10. Western Blot analysis of DAB2IP expression in HepG2.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DAB2IP is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — DAB2IP
Entrez GeneID
153090GeneBank Accession#
NM_032552Protein Accession#
NP_115941.1Gene Name
DAB2IP
Gene Alias
AF9Q34, AIP1, DIP1/2, FLJ39072, KIAA1743
Gene Description
DAB2 interacting protein
Omim ID
609205Gene Ontology
HyperlinkGene Summary
DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM
Other Designations
ASK-interacting protein|ASK1-interacting protein 1|DOC-2/DAB2 interactive protein|OTTHUMP00000022026|OTTHUMP00000022028|disabled homolog 2 interacting protein|nGAP-like protein
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Interactome
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Disease
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