PPM1L (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PPM1L full-length ORF ( NP_640338.2, 1 a.a. - 360 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
67.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PPM1L
Entrez GeneID
151742GeneBank Accession#
NM_139245.2Protein Accession#
NP_640338.2Gene Name
PPM1L
Gene Alias
MGC132545, MGC132547, PP2C-epsilon, PP2CE, PPM1-LIKE
Gene Description
protein phosphatase 1 (formerly 2C)-like
Gene Ontology
HyperlinkGene Summary
PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular stimuli (Jin et al., 2004 [PubMed 15560375]).[supplied by OMIM
Other Designations
PP2C epsilon|protein phosphatase 2C epsilon
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Interactome
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Disease
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