PPM1L rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PPM1L peptide using ARM Technology.
Immunogen
A synthetic peptide of human PPM1L is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PPM1L peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PPM1L
Entrez GeneID
151742GeneBank Accession#
PPM1LGene Name
PPM1L
Gene Alias
MGC132545, MGC132547, PP2C-epsilon, PP2CE, PPM1-LIKE
Gene Description
protein phosphatase 1 (formerly 2C)-like
Gene Ontology
HyperlinkGene Summary
PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular stimuli (Jin et al., 2004 [PubMed 15560375]).[supplied by OMIM
Other Designations
PP2C epsilon|protein phosphatase 2C epsilon
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Interactome
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