TTL monoclonal antibody (M02), clone 1B2
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TTL is 0.1 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TTL.
Immunogen
TTL (NP_714923, 279 a.a. ~ 377 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LESSILLQIKHIIRNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFPPPDVEQPQTQPAAFIKL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TTL is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — TTL
Entrez GeneID
150465GeneBank Accession#
NM_153712Protein Accession#
NP_714923Gene Name
TTL
Gene Alias
MGC46235
Gene Description
tubulin tyrosine ligase
Omim ID
608291Gene Ontology
HyperlinkGene Summary
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM
Other Designations
2410003M22Rik|tubulin-tyrosine ligase
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Interactome
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Disease
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