SIK1 monoclonal antibody (M01), clone 2C12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SIK1.
Immunogen
SIK1 (AAH38504.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLY
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SIK1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SIK1 is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SIK1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SIK1
Entrez GeneID
150094GeneBank Accession#
BC038504Protein Accession#
AAH38504.1Gene Name
SIK1
Gene Alias
MSK, SIK, SNF1LK
Gene Description
salt-inducible kinase 1
Omim ID
605705Gene Ontology
HyperlinkOther Designations
SNF1-like kinase|myocardial SNF1-like kinase|serine/threonine protein kinase
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Interactome
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Disease
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Publication Reference
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De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies.
Hansen J, Snow C, Tuttle E, Ghoneim DH, Yang CS, Spencer A, Gunter SA, Smyser CD, Gurnett CA, Shinawi M, Dobyns WB, Wheless J, Halterman MW, Jansen LA, Paschal BM, Paciorkowski AR.
American Journal of Human Genetics 2015 Apr; 96(4):682.
Application:IF, Human, Brain.
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De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies.
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