PYHIN1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PYHIN1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PYHIN1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PYHIN1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PYHIN1
Entrez GeneID
149628GeneBank Accession#
PYHIN1Gene Name
PYHIN1
Gene Alias
IFIX, MGC23885, RP11-520H16.1
Gene Description
pyrin and HIN domain family, member 1
Gene Ontology
HyperlinkGene Summary
PYHIN1 belongs to the HIN200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-terminal ends. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis (Ding et al., 2006 [PubMed 16479015]).[supplied by OMIM
Other Designations
OTTHUMP00000035198|OTTHUMP00000035199|interferon-inducible protein X
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Interactome
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Disease
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