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Last updated: 2017/10/22

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HFE2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00148738-T01
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-HFE2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 33.7
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-HFE2 antibody (H00148738-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00148738-T01
    HFE2 transfected lysate.
    Western Blot
    QC Testing of H00148738-T01
    Lane 1: HFE2 transfected lysate ( 33.7 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Protein Accession#:
  • -
  • Gene Name:
  • HFE2
  • Gene Alias:
  • HFE2A,HJV,JH,MGC23953,RGMC
  • Gene Description:
  • hemochromatosis type 2 (juvenile)
  • Gene Summary:
  • The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000015582,OTTHUMP00000015583,OTTHUMP00000059680,RGM domain family, member C,hemochromatosis type 2 protein,hemojuvelin
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