EME1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EME1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EME1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EME1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EME1
Entrez GeneID
146956GeneBank Accession#
EME1Gene Name
EME1
Gene Alias
FLJ31364, MMS4L
Gene Description
essential meiotic endonuclease 1 homolog 1 (S. pombe)
Omim ID
610885Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability
Other Designations
essential meiotic endonuclease 1 homolog 1|essential meiotic endonuclease 1 homolog 2|homolog of yeast EME1 endonuclease
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