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Last updated: 2016/10/23

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EME1 rabbit monoclonal antibody

  • Catalog # : H00146956-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human EME1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human EME1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human EME1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • EME1
  • Gene Name:
  • EME1
  • Gene Alias:
  • FLJ31364,MMS4L
  • Gene Description:
  • essential meiotic endonuclease 1 homolog 1 (S. pombe)
  • Gene Summary:
  • This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability
  • Other Designations:
  • essential meiotic endonuclease 1 homolog 1,essential meiotic endonuclease 1 homolog 2,homolog of yeast EME1 endonuclease
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