NRG4 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human NRG4 full-length ORF ( AAH17568, 1 a.a. - 115 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPTDHEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSNLFEAFVALAVLVTLIIGAFYFLCRKGHFQRASSVQYDINLVETSSTSAHHSHEQH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.39
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NRG4
Entrez GeneID
145957GeneBank Accession#
BC017568Protein Accession#
AAH17568Gene Name
NRG4
Gene Alias
DKFZp779N0541, DKFZp779N1944, HRG4
Gene Description
neuregulin 4
Omim ID
610894Gene Ontology
HyperlinkGene Summary
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM
Other Designations
OTTHUMP00000183575|heregulin 4
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Interactome
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Pathway
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Disease
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Publication Reference
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Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia.
Liu SQ, Tefft BJ, Roberts DT, Zhang LQ, Ren Y, Li YC, Huang Y, Zhang D, Phillips HR, Wu YH.
American Journal of Physiology. Heart and Circulatory Physiology 2012 Oct; 303(12):H1446.
Application：ELISA, Mouse, Mouse serum.
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Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia.
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