A2ML1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human A2ML1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPCE
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — A2ML1
Entrez GeneID
144568GeneBank Accession#
BC093840.1Protein Accession#
AAH93840.1Gene Name
A2ML1
Gene Alias
CPAMD9, DKFZp686C1729, DKFZp686D2011, DKFZp686G1812, DKFZp686L1821, DKFZp686O1010, FLJ16045, FLJ25179, FLJ39129, FLJ41597, FLJ41598, FLJ41607
Gene Description
alpha-2-macroglobulin-like 1
Omim ID
610627Gene Ontology
HyperlinkGene Summary
The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM
Other Designations
C3 and PZP-like, alpha-2-macroglobulin domain containing 9|OTTHUMP00000158614
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Interactome
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Disease
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