A2ML1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-A2ML1 full-length
Host
Human
Theoretical MW (kDa)
17.49
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-A2ML1 antibody (H00144568-B01) by Western Blots.
SDS-PAGE Gel
A2ML1 transfected lysate.
Western Blot
Lane 1: A2ML1 transfected lysate ( 17.49 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — A2ML1
Entrez GeneID
144568GeneBank Accession#
BC093840.1Protein Accession#
AAH93840.1Gene Name
A2ML1
Gene Alias
CPAMD9, DKFZp686C1729, DKFZp686D2011, DKFZp686G1812, DKFZp686L1821, DKFZp686O1010, FLJ16045, FLJ25179, FLJ39129, FLJ41597, FLJ41598, FLJ41607
Gene Description
alpha-2-macroglobulin-like 1
Omim ID
610627Gene Ontology
HyperlinkGene Summary
The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM
Other Designations
C3 and PZP-like, alpha-2-macroglobulin domain containing 9|OTTHUMP00000158614
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