VMD2L3 (Human) Recombinant Protein (Q01)

Catalog # H00144453-Q01

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Size:25 ug
Price: USD $ 510.00
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Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

  • Specification

    Product Description

    Human VMD2L3 partial ORF ( NP_689652, 169 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    YEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTST

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.63

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — BEST3

    Entrez GeneID

    144453

    GeneBank Accession#

    NM_152439

    Protein Accession#

    NP_689652

    Gene Name

    BEST3

    Gene Alias

    MGC13168, MGC40411, VMD2L3

    Gene Description

    bestrophin 3

    Omim ID

    607337

    Gene Ontology

    Hyperlink

    Gene Summary

    BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM

    Other Designations

    vitelliform macular dystrophy 2-like 3

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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