C5orf20 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human C5orf20 full-length ORF ( NP_570900.1, 1 a.a. - 244 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MHYGAATHIQNSRSHGLETVPGHQRLERGAGGETPEFPGCHSPAPPENFGNELLPLSAPLQGLSEGLYPPGRNKTLPAGVLREGAVQFLHRGLCNSNLSSEASARPSGTQDELHSSRRKTGQTRREGARKHLVCSFRLYPFTVHTVSPGNSHLALYQVFKAVKLCPSETSFFLSRKSLKSSDPWHPPSLSPNSWNRQAGFRAWSSHLISLSLTCSDSQSRRVSSSQQPPLHSLSSHRRAAHVPE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
53.1
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — C5orf20
Entrez GeneID
140947GeneBank Accession#
NM_130848.1Protein Accession#
NP_570900.1Gene Name
C5orf20
Gene Alias
DCNP1
Gene Description
chromosome 5 open reading frame 20
Omim ID
609710Gene Ontology
HyperlinkGene Summary
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq
Other Designations
dendritic cell nuclear protein 1
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Interactome
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Disease
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