STARD4 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-STARD4 full-length
Host
Human
Theoretical MW (kDa)
23.5
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-STARD4 antibody (H00134429-B01) by Western Blots.
SDS-PAGE Gel
STARD4 transfected lysate.
Western Blot
Lane 1: STARD4 transfected lysate ( 23.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — STARD4
Entrez GeneID
134429GeneBank Accession#
NM_139164Protein Accession#
NP_631903.1Gene Name
STARD4
Gene Alias
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Gene Description
StAR-related lipid transfer (START) domain containing 4
Omim ID
607049Gene Ontology
HyperlinkGene Summary
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM
Other Designations
START domain containing 4 sterol-regulated|START domain containing 4, sterol regulated
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