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Last updated: 2017/5/21

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STARD4 Pre-design Chimera RNAi

  • Catalog # : H00134429-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens START domain containing 4, sterol regulated (STARD4), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_139164
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • STARD4
  • Gene Alias:
  • -
  • Gene Description:
  • StAR-related lipid transfer (START) domain containing 4
  • Gene Summary:
  • Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM
  • Other Designations:
  • START domain containing 4 sterol-regulated,START domain containing 4, sterol regulated
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