ACVR1C 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ACVR1C full-length
Host
Human
Theoretical MW (kDa)
54.34
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ACVR1C antibody (H00130399-B01) by Western Blots.
SDS-PAGE Gel
ACVR1C transfected lysate.
Western Blot
Lane 1: ACVR1C transfected lysate ( 54.34 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ACVR1C
Entrez GeneID
130399GeneBank Accession#
NM_145259.1Protein Accession#
NP_660302.1Gene Name
ACVR1C
Gene Alias
ACVRLK7, ALK7
Gene Description
activin A receptor, type IC
Omim ID
608981Gene Ontology
HyperlinkGene Summary
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
Other Designations
activin receptor-like kinase 7
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Interactome
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Pathway
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Disease
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