ACVR1C purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ACVR1C expression in transfected 293T cell line (H00130399-T01) by ACVR1C MaxPab polyclonal antibody.
Lane 1: ACVR1C transfected lysate(54.23 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ACVR1C protein.
Immunogen
ACVR1C (NP_660302.1, 1 a.a. ~ 493 a.a) full-length human protein.
Sequence
MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERYWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTMAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACVR1C expression in transfected 293T cell line (H00130399-T01) by ACVR1C MaxPab polyclonal antibody.
Lane 1: ACVR1C transfected lysate(54.23 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ACVR1C
Entrez GeneID
130399GeneBank Accession#
NM_145259.1Protein Accession#
NP_660302.1Gene Name
ACVR1C
Gene Alias
ACVRLK7, ALK7
Gene Description
activin A receptor, type IC
Omim ID
608981Gene Ontology
HyperlinkGene Summary
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
Other Designations
activin receptor-like kinase 7
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Interactome
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Pathway
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Disease
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