OSCAR (Human) Recombinant Protein (Q01)

Catalog # H00126014-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human OSCAR partial ORF ( NP_996553.1, 175 a.a. - 254 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    TLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQP

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    34.54

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — OSCAR

    Entrez GeneID

    126014

    GeneBank Accession#

    NM_206817

    Protein Accession#

    NP_996553.1

    Gene Name

    OSCAR

    Gene Alias

    MGC33613, PIGR3

    Gene Description

    osteoclast associated, immunoglobulin-like receptor

    Omim ID

    606862

    Gene Ontology

    Hyperlink

    Gene Summary

    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000067452|osteoclast associated receptor OSCAR-S1|osteoclast associated receptor OSCAR-S2|osteoclast-associated receptor|polymeric immunoglobulin receptor 3

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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