Western blot analysis of MSI2 over-expressed 293 cell line, cotransfected with MSI2 Validated Chimera RNAi ( Cat # H00124540-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MSI2 monoclonal antibody (M08), clone 2D12 (Cat # H00124540-M08 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq