NIPA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NIPA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NIPA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NIPA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NIPA1
Entrez GeneID
123606GeneBank Accession#
NIPA1Gene Name
NIPA1
Gene Alias
FSP3, MGC102724, MGC35570, SPG6
Gene Description
non imprinted in Prader-Willi/Angelman syndrome 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6. [provided by RefSeq
Other Designations
non-imprinted in Prader-Willi/Angelman syndrome 1|spastic paraplegia 6 (autosomal dominant)
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Interactome
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Disease
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