SENP8 rabbit monoclonal antibody

Catalog # H00123228-K

Size

Price

Stock

Quantity

Size:100 ug x up to 3
Price: -
Stock:
made to order, 8 months
abnova-minus
abnova-plus

* The price is valid only in USA. Please select country.

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Rabbit monoclonal antibody raised against a human SENP8 peptide using ARM Technology.

    Immunogen

    A synthetic peptide of human SENP8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.

    Host

    Rabbit

    Library Construction

    Non-fusion antibody library from rabbit spleen (ARM Technology).

    Expression

    Overexpression vector and transfection into 293H cell line.

    Reactivity

    Human

    Purification

    Protein A

    Isotype

    IgG

    Quality Control Testing

    Antibody reactive against human SENP8 peptide by ELISA and mammalian transfected lysate by Western Blot.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

    Deliverable

    Up to three rabbit IgG clones of 100 ug each will be delivered to customer.

    Note

    1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

  • Applications

    Western Blot (Transfected lysate)

    ELISA

  • Gene Info — SENP8

    Entrez GeneID

    123228

    GeneBank Accession#

    SENP8

    Gene Name

    SENP8

    Gene Alias

    DEN1, HsT17512, NEDP1, PRSC2

    Gene Description

    SUMO/sentrin specific peptidase family member 8

    Omim ID

    608659

    Gene Ontology

    Hyperlink

    Gene Summary

    NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM

    Other Designations

    NEDD8-specific protease 1|SUMO/sentrin specific protease family member 8|deneddylase 1|protease, cysteine, 2 (NEDD8 specific)|sentrin/SUMO-specific protease SENP8

Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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