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Last updated: 2018/6/17
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SENP8 MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00123228-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human SENP8 protein.
  • Immunogen:
  • SENP8 (NP_660205.2, 1 a.a. ~ 212 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SENP8 MaxPab rabbit polyclonal antibody. Western Blot analysis of SENP8 expression in human liver.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SENP8 expression in transfected 293T cell line (H00123228-T01) by SENP8 MaxPab polyclonal antibody.

    Lane 1: SENP8 transfected lysate(24.1 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of SENP8 transfected lysate using anti-SENP8 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SENP8 monoclonal antibody (M06), clone 2E1 (H00123228-M06).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • SENP8
  • Gene Alias:
  • DEN1,HsT17512,NEDP1,PRSC2
  • Gene Description:
  • SUMO/sentrin specific peptidase family member 8
  • Gene Summary:
  • NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM
  • Other Designations:
  • NEDD8-specific protease 1,SUMO/sentrin specific protease family member 8,deneddylase 1,protease, cysteine, 2 (NEDD8 specific),sentrin/SUMO-specific protease SENP8
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