LEO1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LEO1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LEO1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LEO1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LEO1
Entrez GeneID
123169GeneBank Accession#
LEO1Gene Name
LEO1
Gene Alias
RDL
Gene Description
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Omim ID
610507Gene Ontology
HyperlinkGene Summary
LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM
Other Designations
Leo1, Paf1/RNA polymerase II complex component, homolog|replicative senescence downregulated leo1-like|senescence downregulated leo1-like
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Interactome
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