TTC8 monoclonal antibody (M03), clone 7E2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TTC8.
Immunogen
TTC8 (NP_653197, 416 a.a. ~ 514 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATISDKIGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLRQHFAM
Host
Mouse
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (93); Rat (83)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TTC8 monoclonal antibody (M03), clone 7E2. Western Blot analysis of TTC8 expression in PC-12 ( Cat # L012V1 ).Western Blot (Cell lysate)
TTC8 monoclonal antibody (M03), clone 7E2 Western Blot analysis of TTC8 expression in NIH/3T3 ( Cat # L018V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — TTC8
Entrez GeneID
123016GeneBank Accession#
NM_144596Protein Accession#
NP_653197Gene Name
TTC8
Gene Alias
BBS8
Gene Description
tetratricopeptide repeat domain 8
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
Bardet-Biedl syndrome type 8
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Interactome
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Disease
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