PPIL5 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
PPIL5 transfected lysate.
Western Blot
Lane 1: PPIL5 transfected lysate ( 45.65 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PPIL5 full-length
Host
Human
Theoretical MW (kDa)
45.65
Interspecies Antigen Sequence
Mouse (77); Rat (77)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PPIL5 antibody (H00122769-B01) by Western Blots.
SDS-PAGE Gel
PPIL5 transfected lysate.
Western Blot
Lane 1: PPIL5 transfected lysate ( 45.65 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PPIL5
Entrez GeneID
122769GeneBank Accession#
NM_152329.3Protein Accession#
NP_689542.2Gene Name
PPIL5
Gene Alias
4-1BBLRR, LRR-1, MGC20689
Gene Description
peptidylprolyl isomerase (cyclophilin)-like 5
Omim ID
609193Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4-1BB-mediated signaling molecule|LRR-repeat protein 1|cyclophilin-like 5|peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3
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