PPIL5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PPIL5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PPIL5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PPIL5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PPIL5
Entrez GeneID
122769GeneBank Accession#
PPIL5Gene Name
PPIL5
Gene Alias
4-1BBLRR, LRR-1, MGC20689
Gene Description
peptidylprolyl isomerase (cyclophilin)-like 5
Omim ID
609193Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4-1BB-mediated signaling molecule|LRR-repeat protein 1|cyclophilin-like 5|peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3
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Interactome
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