ALKBH2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ALKBH2 full-length ORF (NP_001001655.1, 1 a.a. - 261 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.7
Interspecies Antigen Sequence
Mouse (74); Rat (75)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ALKBH2
Entrez GeneID
121642GeneBank Accession#
NM_001001655.1Protein Accession#
NP_001001655.1Gene Name
ALKBH2
Gene Alias
ABH2, MGC90512, hABH2
Gene Description
alkB, alkylation repair homolog 2 (E. coli)
Omim ID
610602Gene Ontology
HyperlinkGene Summary
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM
Other Designations
2OG-Fe(II) oxy DC1|alkB, alkylation repair homolog 2
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Interactome
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Disease
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