ALKBH2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ALKBH2 protein.
Immunogen
ALKBH2 (NP_001001655.1, 1 a.a. ~ 261 a.a) full-length human protein.
Sequence
MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (75)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
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Gene Info — ALKBH2
Entrez GeneID
121642GeneBank Accession#
NM_001001655.1Protein Accession#
NP_001001655.1Gene Name
ALKBH2
Gene Alias
ABH2, MGC90512, hABH2
Gene Description
alkB, alkylation repair homolog 2 (E. coli)
Omim ID
610602Gene Ontology
HyperlinkGene Summary
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM
Other Designations
2OG-Fe(II) oxy DC1|alkB, alkylation repair homolog 2
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Interactome
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Disease
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