CYP2R1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CYP2R1 transfected lysate.
Western Blot
Lane 1: CYP2R1 transfected lysate ( 55.22 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CYP2R1 full-length
Host
Human
Theoretical MW (kDa)
55.22
Interspecies Antigen Sequence
Mouse (88); Rat (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CYP2R1 antibody (H00120227-B01) by Western Blots.
SDS-PAGE Gel
CYP2R1 transfected lysate.
Western Blot
Lane 1: CYP2R1 transfected lysate ( 55.22 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CYP2R1
Entrez GeneID
120227GeneBank Accession#
NM_024514.4Protein Accession#
NP_078790.2Gene Name
CYP2R1
Gene Alias
MGC4663
Gene Description
cytochrome P450, family 2, subfamily R, polypeptide 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq
Other Designations
cytochrome P450, family 2, R1|vitamin D 25-hydroxylase
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Disease
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