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Last updated: 2017/11/19

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EXOSC6 Pre-design Chimera RNAi

  • Catalog # : H00118460-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens exosome component 6 (EXOSC6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_058219
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • EXOSC6
  • Gene Alias:
  • EAP4,MTR3,Mtr3p,hMtr3p,p11
  • Gene Description:
  • exosome component 6
  • Gene Summary:
  • This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq
  • Other Designations:
  • Mtr3 (mRNA transport regulator 3)-homolog,OTTHUMP00000174902,homolog of yeast mRNA transport regulator 3
  • Gene Pathway
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