SH2D1B monoclonal antibody (M04), clone 2B4
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of SH2D1B transfected lysate using anti-SH2D1B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SH2D1B MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SH2D1B is 0.3 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SH2D1B.
Immunogen
SH2D1B (NP_444512.2, 54 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RIFREKHGYYRIQTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLKLELETFVNSNSDYVDVLP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (65); Rat (65)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of SH2D1B transfected lysate using anti-SH2D1B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SH2D1B MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SH2D1B is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SH2D1B
Entrez GeneID
117157GeneBank Accession#
NM_053282Protein Accession#
NP_444512.2Gene Name
SH2D1B
Gene Alias
EAT2
Gene Description
SH2 domain containing 1B
Omim ID
608510Gene Ontology
HyperlinkGene Summary
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM
Other Designations
OTTHUMP00000029531|SH2 domain-containing molecule EAT2
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Interactome
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Pathway
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