THEM4 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human THEM4 partial ORF ( NP_444283.2, 179 a.a. - 240 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NLNINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSLT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.56
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — THEM4
Entrez GeneID
117145GeneBank Accession#
NM_053055Protein Accession#
NP_444283.2Gene Name
THEM4
Gene Alias
CTMP, MGC29636
Gene Description
thioesterase superfamily member 4
Omim ID
606388Gene Ontology
HyperlinkGene Summary
Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq
Other Designations
C-terminal modulator protein|OTTHUMP00000015248
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