APOA5 MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human APOA5 protein.
Immunogen
APOA5 (AAI01790.1, 1 a.a. ~ 366 a.a) full-length human protein.
Sequence
MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (71)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of APOA5 expression in transfected 293T cell line (H00116519-T01) by APOA5 MaxPab polyclonal antibody.
Lane 1: APOA5 transfected lysate(40.26 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — APOA5
Entrez GeneID
116519GeneBank Accession#
NM_052968.3Protein Accession#
AAI01790.1Gene Name
APOA5
Gene Alias
APOA-V, APOAV, MGC126836, MGC126838, RAP3
Gene Description
apolipoprotein A-V
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an apolipoprotein and an important determinant of plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. This gene uses alternate polyadenylation sites and is located proximal to the apolipoprotein gene cluster on chromosome 11q23. [provided by RefSeq
Other Designations
apolipoprotein A-V precursor variant 1|apolipoprotein A-V precursor variant 2|apolipoprotein A5|apolipoprotein AV|regeneration-associated protein 3
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Interactome
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Pathway
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Disease
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Publication Reference
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Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake.
van den Berg SA, Heemskerk MM, Geerling JJ, van Klinken JB, Schaap FG, Bijland S, Berbee JF, van Harmelen VJ, Pronk AC, Schreurs M, Havekes LM, Rensen PC, van Dijk KW.
FASEB Journal 2013 Aug; 27(8):3354.
Application:Injection, Recombinant protein.
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Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake.
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