PHACTR3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PHACTR3 full-length ORF ( NP_899069.1, 1 a.a. - 448 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
77.9
Interspecies Antigen Sequence
Mouse (75); Rat (76)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PHACTR3
Entrez GeneID
116154GeneBank Accession#
NM_183246.1Protein Accession#
NP_899069.1Gene Name
PHACTR3
Gene Alias
C20orf101, H17739, MGC117178, SCAPIN1, SCAPININ
Gene Description
phosphatase and actin regulator 3
Omim ID
608725Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000031424|OTTHUMP00000174466|OTTHUMP00000174467|phosphatase and actin regulator 3, isoform 1|scaffold-associated PP1 inhibiting protein
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Interactome
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Disease
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