PHACTR3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PHACTR3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PHACTR3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PHACTR3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PHACTR3
Entrez GeneID
116154GeneBank Accession#
PHACTR3Gene Name
PHACTR3
Gene Alias
C20orf101, H17739, MGC117178, SCAPIN1, SCAPININ
Gene Description
phosphatase and actin regulator 3
Omim ID
608725Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000031424|OTTHUMP00000174466|OTTHUMP00000174467|phosphatase and actin regulator 3, isoform 1|scaffold-associated PP1 inhibiting protein
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Interactome
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Disease
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