TMEM123 monoclonal antibody (M02), clone 1F4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of TMEM123 expression in transfected 293T cell line by TMEM123 monoclonal antibody (M02), clone 1F4.
Lane 1: TMEM123 transfected lysate (Predicted MW: 21.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TMEM123.
Immunogen
TMEM123 (NP_443164, 34 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTAASNTTTPGMVSTNMTSTTLKSTPKTTSVSQNTSQISTSTMTVTHNSSVTSAASSVTITT
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TMEM123 expression in transfected 293T cell line by TMEM123 monoclonal antibody (M02), clone 1F4.
Lane 1: TMEM123 transfected lysate (Predicted MW: 21.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — TMEM123
Entrez GeneID
114908GeneBank Accession#
NM_052932Protein Accession#
NP_443164Gene Name
TMEM123
Gene Alias
KCT3, PORIMIN, PORMIN
Gene Description
transmembrane protein 123
Omim ID
606356Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq
Other Designations
keratinocytes associated transmembrane protein 3|pro oncosis receptor inducing membrane injury|pro-oncosis receptor inducing membrane injury|serine/threonine-rich receptor
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