TMEM123 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of TMEM123 expression in transfected 293T cell line (H00114908-T01) by TMEM123 MaxPab polyclonal antibody.
Lane 1: TMEM123 transfected lysate(22.88 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TMEM123 protein.
Immunogen
TMEM123 (NP_443164.2, 1 a.a. ~ 208 a.a) full-length human protein.
Sequence
MGLGARGAWAALLLGTLQVLALLGAAHESAAMAASANIENSGLPHNSSANSTETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTAASNTTTPGMVSTNMTSTTLKSTPKTTSVSQNTSQISTSTMTVTHNSSVTSAASSVTITTTMHSEAKKGSKFDTGSFVGGIVLTLGVLSILYIGCKMYYSRRGIRYRTIDEHDAII
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TMEM123 expression in transfected 293T cell line (H00114908-T01) by TMEM123 MaxPab polyclonal antibody.
Lane 1: TMEM123 transfected lysate(22.88 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TMEM123
Entrez GeneID
114908GeneBank Accession#
NM_052932.2Protein Accession#
NP_443164.2Gene Name
TMEM123
Gene Alias
KCT3, PORIMIN, PORMIN
Gene Description
transmembrane protein 123
Omim ID
606356Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq
Other Designations
keratinocytes associated transmembrane protein 3|pro oncosis receptor inducing membrane injury|pro-oncosis receptor inducing membrane injury|serine/threonine-rich receptor
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