FBXO32 293T Cell Transient Overexpression Lysate(Denatured)

Catalog # H00114907-T01

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Size:100 uL
Price: USD $ 247.00
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Images
SDS-PAGE Gel
QC Test

SDS-PAGE Gel

FBXO32 transfected lysate.

Western Blot
QC Test

Western Blot

Lane 1: FBXO32 transfected lysate ( 39.16 KDa)
Lane 2: Non-transfected lysate.

  • Specification

    Transfected Cell Line

    293T

    Plasmid

    pCMV-FBXO32 full-length

    Host

    Human

    Theoretical MW (kDa)

    39.16

    Interspecies Antigen Sequence

    Mouse (96); Rat (95)

    Quality Control Testing

    Transient overexpression cell lysate was tested with Anti-FBXO32 antibody (H00114907-B01) by Western Blots.

    SDS-PAGE Gel

    FBXO32 transfected lysate.

    Western Blot

    Lane 1: FBXO32 transfected lysate ( 39.16 KDa)
    Lane 2: Non-transfected lysate.

    Storage Buffer

    1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

  • Gene Info — FBXO32

    Entrez GeneID

    114907

    GeneBank Accession#

    NM_058229.2

    Protein Accession#

    ENSP00000287396

    Gene Name

    FBXO32

    Gene Alias

    FLJ32424, Fbx32, MAFbx, MGC33610

    Gene Description

    F-box protein 32

    Omim ID

    606604

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes. [provided by RefSeq

    Other Designations

    F-box only protein 32|atrogin 1|muscle atrophy F-box protein

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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