GNRHR2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human GNRHR2 partial ORF ( NP_001457, 237 a.a. - 292 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TLGCRRGHQELSIDSSKEGSGRMLQEEIHAFRQLEVQKTVTSRRAGETKGISITSI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
31.9
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GNRHR2
Entrez GeneID
114814GeneBank Accession#
NM_057163Protein Accession#
NP_001457Gene Name
GNRHR2
Gene Alias
GnRH-II-R
Gene Description
gonadotropin-releasing hormone (type 2) receptor 2
Gene Ontology
HyperlinkGene Summary
The receptor for gonadotropin releasing hormone 2 (GnRH2) is encoded by the GnRH2 receptor (GnRHR2) gene. In non-hominoid primates and non-mammalian vertebrates, GnRHR2 encodes a seven-transmembrane G-protein coupled receptor. However, in human, the N-terminus of the predicted protein contains a frameshift and premature stop codon. In human, GnRHR2 transcription occurs but whether the gene produces a functional C-terminal multi-transmembrane protein is currently unresolved. Alternative splice variants have been reported. An untranscribed pseudogene of GnRHR2 is also on chromosome 14. [provided by RefSeq
Other Designations
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Disease
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